Associate Scientist, Upstream Development

Position Summary:

Frontera Therapeutics is seeking an Associate Scientist to join our Upstream Process Development Team. This individual will help progress gene therapy portfolio programs into the clinical stage. This successful candidate will execute process development and characterization studies using shake flasks and bench-top bioreactors, participate in scale-up efforts, and transfer processes to CDMO/CMOs. This person will interact extensively with other groups within Frontera, including Downstream and Analytical teams.

Key Responsibilities

  • Contribute to experimental design and execute laboratory experiments with minimal supervision
  • Perform data analysis on the performed and related activities and prepare technical reports, SOPs, and internal and external presentations
  • Assist with development activities at CDMOs and support technology transfer efforts including knowledge transfer, scale-up, facility gap analysis
  • Ensure effective, high-quality, timely, and appropriate documentation in electronic laboratory notebooks
  • Effectively maintain good communication and collaborate with cross-functional colleagues for successful execution/completion of the project
  • Support maintenance activities for laboratory function, including preventative maintenance, raw material management, and media preparation

Required Education, Experience, Skills & Competencies

  • B.S, M.S in Chemical Engineering, Biochemical Engineering, Biochemistry or equivalent related fields with 0-3+ years of relevant industrial experience required
  • Strong hands-on experience or knowledge of cell culture, aseptic technique, analytical instrumentation (such as cell counters and metabolite analyzer), and bioreactor operations is required
  • Experience with viral vector production, statistical software, technology transfer to CDMO/manufacturing facility, and process characterization experience is a plus
  • Strong communication skills, including writing and oral presentations
  • Strong technical and analytical skills
  • Take initiative, being willing to work in a fast-paced environment with demonstrated capacity to handle multiple tasks and demands
  • Pro-active attitude, flexible, professional, independent, and a team player

If interested in this position, contact us at